AIDS Vaccine for Asia Network (AVAN): Expanding the Regional Role in Developing HIV Vaccines

Kent SJ, Cooper DA, Chhi Vun M, Shao Y, Zhang L, et al. (2010) AIDS Vaccine for Asia Network (AVAN): Expanding the Regional Role in Developing HIV Vaccines. PLoS Med 7(9): e1000331. doi:10.1371/journal.pmed.1000331


The HIV/AIDS pandemic continues to spread and an AIDS vaccine is urgently needed. While facing unprecedented challenges, AIDS vaccine development activities are continuing around the globe. Recent results of the Thai Phase III vaccine trial are renewing such efforts. In accordance with the goals of the Global HIV Vaccine Enterprise, there is now clear recognition of the role that regional alliances can play in fostering and facilitating AIDS vaccine development, and there is broad agreement that international collaborations are the most effective way forward to develop and evaluate the next generation of AIDS vaccine candidates.

In response to these challenges, the Asian region has recently formed the AIDS Vaccine for Asia Network (AVAN).

AVAN has been initiated to meet these needs and actively facilitate the development of a regional AIDS vaccine strategy that accelerates research and development of an AIDS vaccine through government advocacy, improved coordination and harmonization of research; develops clinical trial and manufacturing capacity; supports ethical and regulatory frameworks; and ensures community participation.