David Diemert of George Washington Unversity and his collaborators in Brazil used an informational video to explain a hookworn vaccine trial in the rural community of Minas Gerais in Southeastern Brazil. The group measured attitudes, fears, and perceptions through a structured questionnaire before and after the clinical trial.
In the paper, they observed that video materials were a successful tool among patients in resource-limited populations to increase understanding about the purpose of vaccination and possible adverse effects of a novel vaccine under study. Although more than 90% said that they would participate in a hookworm vaccine trial, an increase in the number who expressed fear of being vaccinated with an experimental vaccine was seen after viewing the video (51.4% post-video versus 29.2% pre-video).
The group concluded that educational tools can be specially designed to significantly improve understanding and likelihood of obtaining truly informed consent for participation in clinical research.
read full article: Gazzinelli, et al. 2010. CT educ thru analogies
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